Kisspeptin

Kisspeptin is a natural peptide signal that plays a major role in the body's reproductive hormone system. It activates the KISS1 receptor, which helps turn on GnRH. GnRH then helps control the release of LH and FSH, two key hormones in fertility and reproductive function. Researchers study kisspeptin in areas such as puberty, fertility, hormone timing, ovarian function, testicular biology, and how metabolism can affect reproductive signals. Because kisspeptin sits near the top of this hormone chain, it gives researchers a direct way to study how the brain controls many parts of reproductive hormone activity.